Tag Archives: neurodegeneration

Parkinson’s Vax Enters Clinical Trials | The Scientist

Parkinson’s Vax Enters Clinical Trials | The Scientist.

In what is possibly the biggest news of the year, scientists in Vienna are entering trials to vaccinate people against Parkinson’s Disease. The method is based upon building an immune response to alfa-synuclein, a protein naturally produced by the body. This smacks of the potential for massive organ failure due to a massive auto-immune response, akin to what we saw in the early days of gene therapy. I hope I’m wrong…

Here is the full press release: http://www.affiris.com/html/en/presse_medien/pressemeldungen.html

via Parkinson’s Vax Enters Clinical Trials | The Scientist.

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Telomeres predict lifespan in Zebra Finches, Neural proteins a lynchpin in neurodegenerative disease

Two bits of news out in the past few days. Although the theory that telomeres (the tips of chromosomes) play a role in organismal aging has taken hits in the past decade, a paper out in Proceedings of the National Academy of Sciences presents evidence that telomere length in early life reliably predicted lifespan in a population in zebra finches. Popular science article.

Scientists at the Salk Institute for Biological Studies have discovered a neural protein that appears never to be replaced. In the rats they studied, these transport proteins appear to be as old as the rats themselves. The discovery has led the investigator to hypothesize that damage to the proteins may lead to aging and neurodegeneration. Read the popular science article here.